Identification of Epithelial Phospholipase A2 Receptor 1 as a Potential Target in Asthma

Identification of Epithelial Phospholipase A2 Receptor 1 as a Potential Target in Asthma

Secreted phospholipase A 2 s (sPLA 2 s) regulate eicosanoid formation and have been implicated in asthma. Although sPLA 2 s function as enzymes, some of the sPLA 2 s bind with high affinity to a C-type lectin receptor, called PLA 2 R1, which has functions in both cellular signaling and clearance of...

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Bibliographic Details
Main Authors: Nolin, J., Ogden, H., Lai, Y., Altemeier, W., Frevert, C., Bollinger, J., Naika, G., Kicic, Anthony, Stick, S., Lambeau, G., Henderson, W., Gelb, M., Hallstrand, T.
Format: Journal Article
Published: American Lung Association 2016
Online Access:http://hdl.handle.net/20.500.11937/57210

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