Identification of Epithelial Phospholipase A2 Receptor 1 as a Potential Target in Asthma
Secreted phospholipase A 2 s (sPLA 2 s) regulate eicosanoid formation and have been implicated in asthma. Although sPLA 2 s function as enzymes, some of the sPLA 2 s bind with high affinity to a C-type lectin receptor, called PLA 2 R1, which has functions in both cellular signaling and clearance of...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Journal Article |
| Published: |
American Lung Association
2016
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| Online Access: | http://hdl.handle.net/20.500.11937/57210 |