Insulin resistance is associated with reductions in specific cognitive domains and increases in CSF tau in cognitively normal adults

Insulin resistance is associated with reductions in specific cognitive domains and increases in CSF tau in cognitively normal adults

Growing evidence supports the hypothesis that type 2 diabetes (T2D) increases the risk of developing dementia. Experimental evidence from mouse models demonstrates that the induction of T2D/insulin resistance (IR) can promote the accumulation of Alzheimer's disease (AD) pathological features. H...

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Bibliographic Details
Main Authors: Laws, S., Gaskin, S., Woodfield, A., Srikanth, V., Bruce, D., Fraser, P., Porter, T., Newsholme, Philip, Wijesekara, N., Burnham, S., Doré, V., Li, Q., Maruff, P., Masters, C., Rainey-Smith, S., Rowe, C., Salvado, O., Villemagne, V., Martins, R., Verdile, Giuseppe
Format: Journal Article
Published: Nature Publishing Group 2017
Online Access:http://purl.org/au-research/grants/nhmrc/1105698
http://hdl.handle.net/20.500.11937/57036

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