Insulin resistance is associated with reductions in specific cognitive domains and increases in CSF tau in cognitively normal adults

Growing evidence supports the hypothesis that type 2 diabetes (T2D) increases the risk of developing dementia. Experimental evidence from mouse models demonstrates that the induction of T2D/insulin resistance (IR) can promote the accumulation of Alzheimer's disease (AD) pathological features. H...

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Bibliographic Details
Main Authors: Laws, S., Gaskin, S., Woodfield, A., Srikanth, V., Bruce, D., Fraser, P., Porter, T., Newsholme, Philip, Wijesekara, N., Burnham, S., Doré, V., Li, Q., Maruff, P., Masters, C., Rainey-Smith, S., Rowe, C., Salvado, O., Villemagne, V., Martins, R., Verdile, Giuseppe
Format: Journal Article
Published: Nature Publishing Group 2017
Online Access:http://purl.org/au-research/grants/nhmrc/1105698
http://hdl.handle.net/20.500.11937/57036