UV Irradiation of Skin Enhances Glycolytic Flux and Reduces Migration Capabilities in Bone Marrow–Differentiated Dendritic Cells

A systemic immunosuppression follows UV irradiation of the skin of humans and mice. In this study, dendritic cells (DCs) differentiating from the bone marrow (BM) of UV-irradiated mice had a reduced ability to migrate toward the chemokine (C-C motif) ligand 21. Fewer DCs also accumulated in the peri...

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Bibliographic Details
Main Authors: McGonigle, T., Keane, Kevin, Ghaly, S., Carter, K., Anderson, D., Scott, N., Goodridge, H., Dwyer, A., Greenland, E., Pixley, F., Newsholme, Philip, Hart, P.
Format: Journal Article
Published: Elsevier Inc. 2017
Online Access:http://hdl.handle.net/20.500.11937/56863