Patched 1 and Patched 2 redundancy has a key Role in regulating epidermal differentiation

Patched 1 and Patched 2 redundancy has a key Role in regulating epidermal differentiation

The Patched 1 (Ptch1) receptor has a pivotal role in inhibiting the activity of the Hedgehog (Hh) pathway and is therefore critical in preventing the onset of many human developmental disorders and tumor formation. However, the functional role of the mammalian Ptch2 paralogue remains elusive, partic...

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Bibliographic Details
Main Authors: Adolphe, C., Nieuwenhuis, E., Villani, R., Li, Z., Kaur, Pritinder, Hui, C., Wainwright, B.
Format: Journal Article
Published: Nature Publishing Group 2014
Online Access:http://hdl.handle.net/20.500.11937/56752

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