Patched 1 and Patched 2 redundancy has a key Role in regulating epidermal differentiation
The Patched 1 (Ptch1) receptor has a pivotal role in inhibiting the activity of the Hedgehog (Hh) pathway and is therefore critical in preventing the onset of many human developmental disorders and tumor formation. However, the functional role of the mammalian Ptch2 paralogue remains elusive, partic...
| Main Authors: | , , , , , , |
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| Format: | Journal Article |
| Published: |
Nature Publishing Group
2014
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| Online Access: | http://hdl.handle.net/20.500.11937/56752 |