The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis

Background: The establishment and maintenance of polarity is vital for embryonic development and loss of polarity is a frequent characteristic of epithelial cancers, however the underlying molecular mechanisms remain unclear. Here, we identify a novel role for the polarity protein Scrib as a mediato...

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Bibliographic Details
Main Authors: Pearson, H., McGlinn, E., Phesse, T., Schluter, H., Srikumar, A., Godde, N., Woelwer, C., Ryan, A., Phillips, W., Ernst, M., Kaur, Pritinder, Humbert, P.
Format: Journal Article
Published: BioMed Central Ltd. 2015
Online Access:http://hdl.handle.net/20.500.11937/56698