Amidoalkylindoles as Potent and Selective Cannabinoid Type 2 Receptor Agonists with in Vivo Efficacy in a Mouse Model of Multiple Sclerosis

Selective CB 2 agonists represent an attractive therapeutic strategy for the treatment of a variety of diseases without psychiatric side effects mediated by the CB 1 receptor. We carried out a rational optimization of a black market designer drug SDB-001 that led to the identification of potent an...

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Bibliographic Details
Main Authors: Shi, Y., Duan, Y., Ji, Y., Wang, Z., Wu, Y., Gunosewoyo, Hendra, Xie, X., Chen, J., Yang, F., Li, J., Tang, J., Yu, L.
Format: Journal Article
Published: American Chemical Society 2017
Online Access:http://hdl.handle.net/20.500.11937/56683