Amyloid-ß and islet amyloid pathologies link Alzheimer disease and type 2 diabetes in a transgenic model.

Alzheimer's disease (AD) and type 2 diabetes (T2D) present a significant risk to each other. AD and T2D are characterized by deposition of cerebral amyloid-ß (Aß) and pancreatic human islet amyloid polypeptide (hIAPP), respectively. We investigated the role of amyloidogenic proteins in the inte...

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Bibliographic Details
Main Authors: Wijesekara, N., Ahrens, R., Sabale, M., Wu, L., Ha, K., Verdile, Giuseppe, Fraser, P.
Format: Journal Article
Published: Federation of American Societies for Experimental Biology 2017
Online Access:http://hdl.handle.net/20.500.11937/56653