Increased CTLA-4+ T cells may contribute to impaired T helper type 1 immune responses in patients with chronic obstructive pulmonary disease

Impaired T helper type 1 (Th1) function is implicated in the susceptibility of patients with chronic obstructive pulmonary disease (COPD) to respiratory infections, which are common causes of acute exacerbations of COPD (AECOPD). To understand the underlying mechanisms, we assessed regulatory T (Tre...

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Bibliographic Details
Main Authors: Tan, D., Teo, T., Setiawan, A., Ong, N., Zimmermann, M., Price, Patricia, Kirkham, L., Moodley, Y.
Format: Journal Article
Published: 2017
Online Access:http://hdl.handle.net/20.500.11937/56648