Studies of the benzopyran class of selective COX-2 inhibitors using 3D-QSAR and molecular docking

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Studies of the benzopyran class of selective COX-2 inhibitors using 3D-QSAR and molecular docking

Abstract: The Gaussian-based 3D-QSAR studies for 58 selective COX-2 (cyclooxygenase-2) inhibitors belonging to benzopyran chemical class were performed. Partial least squares analysis produced statistically significant model with (R training 2 = 0.866) and predictability (Q training 2 = 0.66, Q test...

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Bibliographic Details
Main Authors:	Yadav, D., Saloni, Sharma, P., Misra, S., Singh, H., Mancera, Ricardo, Kim, K., Jang, C., Kim, M., Pérez-Sánchez, H., Choi, E., Kumar, S.
Format:	Journal Article
Published:	Pharmaceutical Society of Korea 2017
Online Access:	http://hdl.handle.net/20.500.11937/56633

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