Studies of the benzopyran class of selective COX-2 inhibitors using 3D-QSAR and molecular docking
Abstract: The Gaussian-based 3D-QSAR studies for 58 selective COX-2 (cyclooxygenase-2) inhibitors belonging to benzopyran chemical class were performed. Partial least squares analysis produced statistically significant model with (R training 2 = 0.866) and predictability (Q training 2 = 0.66, Q test...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Journal Article |
| Published: |
Pharmaceutical Society of Korea
2017
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| Online Access: | http://hdl.handle.net/20.500.11937/56633 |