Novel biotinylated bile acid amphiphiles: Micellar aggregates formation and interaction with hepatocytes

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Novel biotinylated bile acid amphiphiles: Micellar aggregates formation and interaction with hepatocytes

Amphiphilic bile acids linked through an oligoethylene glycol to a biotin moiety were synthesized and shown to create micellar structures in aqueous environment, interact with avidin and be efficiently incorporated into hepatocyte cells, suggesting their potential as a drug delivery system against l...

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Bibliographic Details
Main Authors:	Rizzi, L., Braschi, M., Colombo, M., Vaiana, N., Tibolla, G., Norata, Giuseppe, Catapano, A., Romeo, S., Prosperi, D.
Format:	Journal Article
Published:	Royal Society of Chemistry 2011
Online Access:	http://hdl.handle.net/20.500.11937/56167

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