Novel biotinylated bile acid amphiphiles: Micellar aggregates formation and interaction with hepatocytes
Amphiphilic bile acids linked through an oligoethylene glycol to a biotin moiety were synthesized and shown to create micellar structures in aqueous environment, interact with avidin and be efficiently incorporated into hepatocyte cells, suggesting their potential as a drug delivery system against l...
| Main Authors: | , , , , , , , , |
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| Format: | Journal Article |
| Published: |
Royal Society of Chemistry
2011
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| Online Access: | http://hdl.handle.net/20.500.11937/56167 |