Novel biotinylated bile acid amphiphiles: Micellar aggregates formation and interaction with hepatocytes
Amphiphilic bile acids linked through an oligoethylene glycol to a biotin moiety were synthesized and shown to create micellar structures in aqueous environment, interact with avidin and be efficiently incorporated into hepatocyte cells, suggesting their potential as a drug delivery system against l...
| Main Authors: | , , , , , , , , |
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| Format: | Journal Article |
| Published: |
Royal Society of Chemistry
2011
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| Online Access: | http://hdl.handle.net/20.500.11937/56167 |
| _version_ | 1848759803313127424 |
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| author | Rizzi, L. Braschi, M. Colombo, M. Vaiana, N. Tibolla, G. Norata, Giuseppe Catapano, A. Romeo, S. Prosperi, D. |
| author_facet | Rizzi, L. Braschi, M. Colombo, M. Vaiana, N. Tibolla, G. Norata, Giuseppe Catapano, A. Romeo, S. Prosperi, D. |
| author_sort | Rizzi, L. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Amphiphilic bile acids linked through an oligoethylene glycol to a biotin moiety were synthesized and shown to create micellar structures in aqueous environment, interact with avidin and be efficiently incorporated into hepatocyte cells, suggesting their potential as a drug delivery system against liver diseases. © 2011 The Royal Society of Chemistry. |
| first_indexed | 2025-11-14T10:05:41Z |
| format | Journal Article |
| id | curtin-20.500.11937-56167 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:05:41Z |
| publishDate | 2011 |
| publisher | Royal Society of Chemistry |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-561672018-03-29T09:09:01Z Novel biotinylated bile acid amphiphiles: Micellar aggregates formation and interaction with hepatocytes Rizzi, L. Braschi, M. Colombo, M. Vaiana, N. Tibolla, G. Norata, Giuseppe Catapano, A. Romeo, S. Prosperi, D. Amphiphilic bile acids linked through an oligoethylene glycol to a biotin moiety were synthesized and shown to create micellar structures in aqueous environment, interact with avidin and be efficiently incorporated into hepatocyte cells, suggesting their potential as a drug delivery system against liver diseases. © 2011 The Royal Society of Chemistry. 2011 Journal Article http://hdl.handle.net/20.500.11937/56167 10.1039/c0ob00878h Royal Society of Chemistry restricted |
| spellingShingle | Rizzi, L. Braschi, M. Colombo, M. Vaiana, N. Tibolla, G. Norata, Giuseppe Catapano, A. Romeo, S. Prosperi, D. Novel biotinylated bile acid amphiphiles: Micellar aggregates formation and interaction with hepatocytes |
| title | Novel biotinylated bile acid amphiphiles: Micellar aggregates formation and interaction with hepatocytes |
| title_full | Novel biotinylated bile acid amphiphiles: Micellar aggregates formation and interaction with hepatocytes |
| title_fullStr | Novel biotinylated bile acid amphiphiles: Micellar aggregates formation and interaction with hepatocytes |
| title_full_unstemmed | Novel biotinylated bile acid amphiphiles: Micellar aggregates formation and interaction with hepatocytes |
| title_short | Novel biotinylated bile acid amphiphiles: Micellar aggregates formation and interaction with hepatocytes |
| title_sort | novel biotinylated bile acid amphiphiles: micellar aggregates formation and interaction with hepatocytes |
| url | http://hdl.handle.net/20.500.11937/56167 |