Novel biotinylated bile acid amphiphiles: Micellar aggregates formation and interaction with hepatocytes
Amphiphilic bile acids linked through an oligoethylene glycol to a biotin moiety were synthesized and shown to create micellar structures in aqueous environment, interact with avidin and be efficiently incorporated into hepatocyte cells, suggesting their potential as a drug delivery system against l...
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Bibliographic Details
| Main Authors: |
Rizzi, L.,
Braschi, M.,
Colombo, M.,
Vaiana, N.,
Tibolla, G.,
Norata, Giuseppe,
Catapano, A.,
Romeo, S.,
Prosperi, D. |
| Format: | Journal Article
|
| Published: |
Royal Society of Chemistry
2011
|
| Online Access: | http://hdl.handle.net/20.500.11937/56167
|