A Multimodal Spectroscopic Imaging Method To Characterize the Metal and Macromolecular Content of Proteinaceous Aggregates ("Amyloid Plaques").

A Multimodal Spectroscopic Imaging Method To Characterize the Metal and Macromolecular Content of Proteinaceous Aggregates ("Amyloid Plaques").

Alzheimer's disease (AD) is a major international health and economic concern. A key pathological feature of AD is so-called "amyloid-ß-plaques", or "Aß-plaques", which are deposits of aggregated protein, enriched with the Aß fragment of amyloid precursor protein. Despite th...

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Bibliographic Details
Main Authors: Summers, K., Fimognari, N., Hollings, A., Kiernan, M., Lam, Virginie, Tidy, R., Paterson, D., Tobin, M., Takechi, Ryu, George, G., Pickering, I., Mamo, J., Harris, H., Hackett, M.
Format: Journal Article
Published: American Chemical Society 2017
Online Access:http://hdl.handle.net/20.500.11937/56158

Internet

http://hdl.handle.net/20.500.11937/56158

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