Stem cell migration and mechanotransduction on linear stiffness gradient hydrogels
The spatial presentation of mechanical information is a key parameter for cell behavior. We have developed a method of polymerization control in which the differential diffusion distance of unreacted cross-linker and monomer into a prepolymerized hydrogel sink results in a tunable stiffness gradient...
| Main Authors: | Hadden, W., Young, J., Holle, A., McFetridge, M., Kim, Du Yong, Wijesinghe, P., Taylor-Weiner, H., Wen, J., Lee, A., Bieback, K., Vo, Ba-Ngu, Sampson, D., Kennedy, B., Spatz, J., Engler, A., Cho, Y. |
|---|---|
| Format: | Journal Article |
| Published: |
National Academy of Sciences
2017
|
| Online Access: | http://hdl.handle.net/20.500.11937/56114 |
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