Identification of seven loci affecting mean telomere length and their association with disease

Identification of seven loci affecting mean telomere length and their association with disease

Interindividual variation in mean leukocyte telomere length (LTL) is associated with cancer and several age-associated diseases. We report here a genome-wide meta-analysis of 37,684 individuals with replication of selected variants in an additional 10,739 individuals. We identified seven loci, inclu...

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Main Authors: Codd, V., Nelson, C., Albrecht, E., Mangino, M., Deelen, J., Buxton, J., Hottenga, J., Fischer, K., Esko, T., Surakka, I., Broer, L., Nyholt, D., Leach, I., Salo, P., Hägg, S., Matthews, M., Palmen, J., Norata, Giuseppe, O'Reilly, P., Saleheen, D., Amin, N., Balmforth, A., Beekman, M., De Boer, R., Böhringer, S., Braund, P., Burton, P., Craen, A., Denniff, M., Dong, Y., Douroudis, K., Dubinina, E., Eriksson, J., Garlaschelli, K., Guo, D., Hartikainen, A., Henders, A., Houwing-Duistermaat, J., Kananen, L., Karssen, L., Kettunen, J., Klopp, N., Lagou, V., Van Leeuwen, E., Madden, P., Mägi, R., Magnusson, P., Männistö, S., McCarthy, M., Medland, S., Mihailov, E., Montgomery, G., Oostra, B., Palotie, A., Peters, A., Pollard, H., Pouta, A., Prokopenko, I., Ripatti, S., Salomaa, V., Suchiman, H., Valdes, A., Verweij, N., Viñuela, A., Wang, X., Wichmann, H., Widen, E., Willemsen, G., Wright, M., Xia, K., Xiao, X., Van Veldhuisen, D.
Format: Journal Article
Published: Nature Publishing Group 2013
Online Access:http://hdl.handle.net/20.500.11937/55728

Internet

http://hdl.handle.net/20.500.11937/55728

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