A CYP26B1 polymorphism enhances retinoic acid catabolism and may aggravate atherosclerosis.

A CYP26B1 polymorphism enhances retinoic acid catabolism and may aggravate atherosclerosis.

All-trans retinoic acid, controlled by cytochrome P450, family 26 (CYP26) enzymes, potentially has beneficial effects in atherosclerosis treatment. This study investigates CYP26 subfamily B, polypeptide 1 (CYP26B1) in atherosclerosis and the effects of a genetic polymorphism in CYP26B1 on retinoid c...

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Bibliographic Details
Main Authors: Krivospitskaya, O., Elmabsout, A., Sundman, E., Söderström, L., Ovchinnikova, O., Gidlöf, A., Scherbak, N., Norata, Giuseppe, Samnegård, A., Törmä, H., Abdel-Halim, S., Jansson, J., Eriksson, P., Sirsjö, A., Olofsson, P.
Format: Journal Article
Published: 2012
Online Access:http://hdl.handle.net/20.500.11937/55580

Internet

http://hdl.handle.net/20.500.11937/55580

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