Biology of proprotein convertase subtilisin kexin 9: Beyond low-density lipoprotein cholesterol lowering

© 2016 The Author. Proprotein convertase subtilisin kexin 9 (PCSK9) is a key regulator of low-density lipoprotein receptor levels and LDL-cholesterol levels. Loss-of-function mutations in PCSK9 gene are associated with hypocholesterolaemia and protection against cardiovascular disease, identifying P...

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Bibliographic Details
Main Authors: Norata, Giuseppe, Tavori, H., Pirillo, A., Fazio, S., Catapano, A.
Format: Journal Article
Published: 2016
Online Access:http://hdl.handle.net/20.500.11937/55517