-374 T/A RAGE Polymorphism Is Associated with Chronic Kidney Disease Progression in Subjects Affected by Nephrocardiovascular Disease
Background: Chronic kidney disease (CKD) patients present elevated advanced glycation end products (AGEs) blood levels. AGEs promote inflammation through binding to their receptor (RAGE), located on the membrane of mesangial cells, endothelial cells and macrophages. Several genetic polymorphisms inf...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal Article |
| Published: |
Public Library of Science
2013
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| Online Access: | http://hdl.handle.net/20.500.11937/55438 |