Statin therapy causes gut dysbiosis in mice through a PXR-dependent mechanism.

BACKGROUND: Statins are a class of therapeutics used to regulate serum cholesterol and reduce the risk of heart disease. Although statins are highly effective in removing cholesterol from the blood, their consumption has been linked to potential adverse effects in some individuals. The most common e...

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Bibliographic Details
Main Authors: Caparrós-Martín, J., Lareu, R., Ramsay, J., Peplies, J., Jerry Reen, F., Headlam, H., Ward, Natalie, Croft, K., Newsholme, P., Hughes, J., O'Gara, F.
Format: Journal Article
Published: 2017
Online Access:http://hdl.handle.net/20.500.11937/55275