Polymorphic variants of SCN1A and EPHX1 influence plasma carbamazepine concentration, metabolism and pharmacoresistance in a population of kosovar albanian epileptic patients
Aim: The present study aimed to evaluate the effects of gene variants in key genes influencing pharmacokinetic and pharmacodynamic of carbamazepine (CBZ) on the response in patients with epilepsy. Materials & Methods: Five SNPs in two candidate genes influencing CBZ transport and metabolism, nam...
| Main Authors: | , , , , , , |
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| Format: | Journal Article |
| Published: |
Public Library of Science
2015
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| Online Access: | http://hdl.handle.net/20.500.11937/55182 |