A potential new, stable state of the E-cadherin strand-swapped dimer in solution

E-cadherin is a transmembrane glycoprotein that facilitates inter-cellular adhesion in the epithelium. The ectodomain of the native structure is comprised of five repeated immunoglobulin-like domains. All E-cadherin crystal structures show the protein in one of three alternative conformations: a mon...

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Bibliographic Details
Main Authors: Schumann-Gillett, A., Mark, A., Deplazes, Evelyne, O'Mara, M.
Format: Journal Article
Published: 2017
Online Access:http://hdl.handle.net/20.500.11937/54511