Structure-based prediction of Wnt binding affinities for Frizzled-type cysteine-rich domain

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Structure-based prediction of Wnt binding affinities for Frizzled-type cysteine-rich domain

Wnt signaling pathways are of significant interest in development and oncogenesis. The first step in these pathways typically involves the binding of a Wnt protein to the cysteine-rich domain (CRD) of a Frizzled receptor; Wnt-Frizzled interactions can be antagonized by secreted Frizzled-related prot...

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Bibliographic Details
Main Authors:	Agostino, M., Öther-Gee Pohl, S., Dharmarajan, Arunasalam
Format:	Journal Article
Published:	The American Society for Biochemistry and Molecular Biology Inc 2017
Online Access:	http://hdl.handle.net/20.500.11937/54450

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