Diabetes and hypertension increase the placental and transcellular permeation of the lipophilic drug diazepam in pregnant women

Background: Previous studies carried out in our laboratories have demonstrated impaired drug permeation in diabetic animals. In this study the permeation of diazepam (after a single dose of 5 mg/day, administered intramuscularly) will be investigated in diabetic and hypertensive pregnant women.Metho...

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Bibliographic Details
Main Authors: Lalic-Popovic, M., Paunkovic, J., Grujic, Z., Golocorbin-Kon, S., Al-Salami, Hani, Mikov, Momir
Format: Journal Article
Published: BioMed Central Ltd 2013
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/5412