14-3-3z regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function

The 14-3-3 family of adaptor proteins regulate diverse cellular functions including cell proliferation, metabolism, adhesion and apoptosis. Platelets express numerous 14-3-3 isoforms, including 14-3- z , which has previously been implicated in regulating GPIb a function. Here we show an important ro...

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Bibliographic Details
Main Authors: Schoenwaelder, S., Darbousset, R., Cranmer, S., Ramshaw, H., Orive, S., Sturgeon, S., Yuan, Y., Yao, Y., Krycer, J., Woodcock, J., Maclean, J., Pitson, S., Zheng, Z., Henstridge, D., van der Wal, D., Gardiner, E., Berndt, Michael, Andrews, R., James, D., Lopez, A., Jackson, S.
Format: Journal Article
Published: Macmillan Publishers Limited 2016
Online Access:http://hdl.handle.net/20.500.11937/53834