Crystallographic analysis of the ternary complex of octanoate and N-acetyl-l-methionine with human serum albumin reveals the mode of their stabilizing interactions

During pasteurization and storage of albumin products, Sodium octanoate (Oct) and N-acethyl-l-tryptophan (N-AcTrp) are used as the thermal stabilizer and the antioxidant for human serum albumin (HSA), respectively. We recently reported that N-acethyl-l-methionine (N-AcMet) is an antioxidant for HSA,...

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Bibliographic Details
Main Authors: Kawai, A., Chuang, Victor, Kouno, Y., Yamasaki, K., Miyamoto, S., Anraku, M., Otagiri, M.
Format: Journal Article
Published: Elsevier BV 2017
Online Access:http://hdl.handle.net/20.500.11937/53781