High-Loading Dose of Microencapsulated Gliclazide Formulation Exerted a Hypoglycaemic Effect on Type 1 Diabetic Rats and Incorporation of a Primary Deconjugated Bile Acid, Diminished the Hypoglycaemic Antidiabetic Effect

Background and objective: Gliclazide is a drug commonly used in type 2 diabetes mellitus. Recently, gliclazide has shown desirable pharmacological effects such as immunoregulatory and anti-clotting effects, which suggests potential applications in type 1 diabetes mellitus (T1DM). Gliclazide has vari...

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Bibliographic Details
Main Authors: Golocorbin-Kon, S., Calasan, J., Milijasevic, B., Vukmirovic, S., Lalic-Popovic, M., Mikov, M., Al-Salami, Hani
Format: Journal Article
Published: Springer France 2017
Online Access:http://hdl.handle.net/20.500.11937/53399