Optimal antimalarial dose regimens for sulfadoxine-pyrimethamine with or without azithromycin in pregnancy based on population pharmacokinetic modeling

Optimal dosing of sulfadoxine-pyrimethamine (SP) as intermittent preventive treatment in pregnancy remains to be established, particularly when coadministered with azithromycin (AZI). To further characterize SP pharmacokinetics in pregnancy, plasma concentration-time data from 45 nonpregnant and 45...

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Bibliographic Details
Main Authors: Salman, S., Baiwog, F., Page-Sharp, Madhu, Griffin, S., Karunajeewa, H., Mueller, I., Rogerson, S., Siba, P., Ilett, K., Davis, T.
Format: Journal Article
Published: American Society for Microbiology 2017
Online Access:http://hdl.handle.net/20.500.11937/52998