Development of tetrahydroisoquinoline analogues: Towards a treatment for Human African Trypanosomiasis

This research describes the exploration of a new scaffold with the potential to be developed in to a new drug for the treatment of Human African Trypanosomiasis (HAT), a neglected disease endemic in sub-Saharan Africa. Derivatives of an isoquinoline scaffold were synthesised and evaluated for their...

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Bibliographic Details
Main Author: Cullen, Danica Renae
Format: Thesis
Published: Curtin University 2016
Online Access:http://hdl.handle.net/20.500.11937/52988