Synthesis, Stereochemistry and Antiparasitic Activity of Derivatives of (4R)-4,6-Dihydroxy-N-methyl-1,2,3,4-tetrahydroisoquinoline
Condensation of phenylephrine with different aldehydes, under Pictet-Spengler cyclisation conditions, afforded a series of tetrahydroisoquinoline derivatives as mixtures of cis/trans isomers. Single crystal X-ray analysis of the dibenzoate derivative of one of the 4-nitrophenyl isomers confirmed it...
| Main Authors: | , , , , , , , |
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| Format: | Journal Article |
| Published: |
Wiley - V C H Verlag GmbH & Co. KGaA
2017
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| Online Access: | http://hdl.handle.net/20.500.11937/52521 |