Breast cancer stem-like cells are inhibited by diosgenin, a steroidal saponin, by the attenuation of the Wnt ß-catenin signaling via the Wnt antagonist secreted frizzled related protein-4

Background: Identification of breast cancer stem cells as the chemo-resistant and tumor-initiating population represents an important milestone in approaching anticancer therapies. Targeting this minor subpopulation of chemo- and radio-resistant stem-like cells, termed as the cancer stem cells (CSCs...

Full description

Bibliographic Details
Main Authors: Bhuvanalakshmi, G., Basappa, Rangappa, K., Dharmarajan, Arunasalam, Sethi, Gautam, Kumar, Alan Prem, Warrier, Sudha
Format: Journal Article
Published: 2017
Online Access:http://hdl.handle.net/20.500.11937/52057