Scoping Studies into the Structure-Activity Relationship (SAR) of Phenylephrine-Derived Analogues as Inhibitors of Trypanosoma brucei rhodesiense

Human African Trypanosomiasis (HAT) is a disease caused by the parasite Trypanosoma brucei and is classified as a neglected tropical disease of concern in sub-Saharan Africa. A scoping study has been undertaken to develop a preliminary structure activity relationship of a tetrahydroisoquinoline scaf...

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Bibliographic Details
Main Authors: Cullen, Danica, Pengon, J., Rattanajak, R., Chaplin, J., Kamchonwongpaisan, S., Mocerino, Mauro
Format: Journal Article
Published: Wiley - V C H Verlag GmbH & Co. KGaA 2016
Online Access:http://hdl.handle.net/20.500.11937/51609