Aberrant localization of apoptosis protease activating factor-1 in lipid raft sub-domains of diffuse large B cell lymphomas

Resistance to chemotherapy remains a challenge in the clinical management of diffuse B cell lymphomas despite aggressive chemotherapy such as CHOP and monoclonal CD20. Here we provide evidence that the apoptosome adaptor protein, Apaf-1, is mislocalized in primary cells derived from patients with di...

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Bibliographic Details
Main Authors: Hirpara, J., Loh, T., Ng, S., Chng, W., Pervaiz, Shazib
Format: Journal Article
Published: Impact Journals LLC 2016
Online Access:http://hdl.handle.net/20.500.11937/51261