hTERT overexpression alleviates intracellular ROS production, improves mitochondrial function, and inhibits ROS-mediated apoptosis in cancer cells

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hTERT overexpression alleviates intracellular ROS production, improves mitochondrial function, and inhibits ROS-mediated apoptosis in cancer cells

The human telomerase reverse transcriptase (hTERT) is the catalytic subunit of the telomerase holoenzyme. Evidence is accumulating to link hTERT to activities other than telomere maintenance and immortalization. Here, we show that hTERT overexpression not only reduces the basal cellular reactive oxy...

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Bibliographic Details
Main Authors:	Indran, I., Hande, M., Pervaiz, Shazib
Format:	Journal Article
Published:	American association for Cancer Research 2011
Online Access:	http://hdl.handle.net/20.500.11937/51251

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