hTERT overexpression alleviates intracellular ROS production, improves mitochondrial function, and inhibits ROS-mediated apoptosis in cancer cells
The human telomerase reverse transcriptase (hTERT) is the catalytic subunit of the telomerase holoenzyme. Evidence is accumulating to link hTERT to activities other than telomere maintenance and immortalization. Here, we show that hTERT overexpression not only reduces the basal cellular reactive oxy...
| Main Authors: | , , |
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| Format: | Journal Article |
| Published: |
American association for Cancer Research
2011
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| Online Access: | http://hdl.handle.net/20.500.11937/51251 |