Oleanolic acid and its synthetic derivatives for the prevention and therapy of cancer: Preclinical and clinical evidence

Oleanolic acid (OA, 3ß-hydroxyolean-12-en-28-oic acid) is a ubiquitous pentacyclic multifunctional triterpenoid, widely found in several dietary and medicinal plants. Natural and synthetic OA derivatives can modulate multiple signaling pathways including nuclear factor-?B, AKT, signal transducer and...

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Bibliographic Details
Main Authors: Shanmugam, M., Dai, X., Kumar, Alan Prem, Tan, B., Sethi, G., Bishayee, A.
Format: Journal Article
Published: Elsevier 2014
Online Access:http://hdl.handle.net/20.500.11937/51203