Differential regulation of sphingolipid metabolism in plasma, hippocampus and cerebral cortex of mice administered sphingolipid modulating agents

Accumulation of ceramide is implicated in mediating the cellular responses to stress and aberrant sphingolipid metabolism is frequently associated with metabolic and neurodegenerative diseases. It is often assumed that (1) peripheral disturbances in sphingolipid concentrations are reflective of proc...

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Bibliographic Details
Main Authors: Giles, Corey, Takechi, Ryu, Mellett, N., Meikle, P., Dhaliwal, Satvinder, Mamo, John
Format: Journal Article
Published: Wiley-Blackwell Publishing Ltd. 2017
Online Access:http://hdl.handle.net/20.500.11937/51196