UV-irradiation of skin enhances glycolytic flux in bone marrow-differentiated dendritic cells

Following UV irradiation of skin, dendritic cells (DCs) differentiating from the bone marrow (BM) of mice have a reduced ability to prime new immune responses; their reduced immunogenicity is maintained for at least 16 weeks in UV-chimeric mice. We hypothesized that different metabolic states underp...

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Bibliographic Details
Main Authors: Hart, P., McGonigle, T., Keane, K., Newsholme, Philip, Ghaly, S., Carter, K., Anderson, D., Scott, N., Goodridge, H.
Format: Conference Paper
Published: WILEY-BLACKWELL 2016
Online Access:http://hdl.handle.net/20.500.11937/51056