The self-association of HMGB1 and its possible role in the binding to DNA and cell membrane receptors

© 2016 Federation of European Biochemical SocietiesHigh mobility group box 1 (HMGB1), a chromatin protein, interacts with DNA and controls gene expression. However, when HMGB1 is released from apoptotic or damaged cells, it triggers proinflammatory reactions by interacting with various receptors, ma...

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Bibliographic Details
Main Authors: Anggayasti, Wresti Listu, Mancera, Ricardo, Bottomley, Steven, Helmerhorst, Erik
Format: Journal Article
Published: Elsevier 2017
Online Access:http://hdl.handle.net/20.500.11937/51012