Biphasic activity of cd137 ligand-stimulated monocytes on T cell apoptosis and proliferation

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Biphasic activity of cd137 ligand-stimulated monocytes on T cell apoptosis and proliferation

CD137L (4-1BBL) is a member of the TNFSF and is expressed on APCs as a transmembrane protein. Reverse signaling by CD137L in monocytes causes cell activation and differentiation to mature inflammatory DCs that can stimulate T cell proliferation. However, CD137L agonists have also been reported to in...

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Bibliographic Details
Main Authors:	Shaqireen Kwajah, M., Mustafa, N., Holme, A., Pervaiz, Shazib, Schwarz, H.
Format:	Journal Article
Published:	Society for Leukocyte Biology 2011
Online Access:	http://hdl.handle.net/20.500.11937/50933

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