Biphasic activity of cd137 ligand-stimulated monocytes on T cell apoptosis and proliferation
CD137L (4-1BBL) is a member of the TNFSF and is expressed on APCs as a transmembrane protein. Reverse signaling by CD137L in monocytes causes cell activation and differentiation to mature inflammatory DCs that can stimulate T cell proliferation. However, CD137L agonists have also been reported to in...
| Main Authors: | , , , , |
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| Format: | Journal Article |
| Published: |
Society for Leukocyte Biology
2011
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| Online Access: | http://hdl.handle.net/20.500.11937/50933 |