Analysis of reproducibility for proteome coverage and quantitation using isobaric mass tags (iTRAQ and TMT)

This study aimed to compare the depth and reproducibility of total proteome and differentially expressed protein coverage in technical duplicates and triplicates using iTRAQ 4-plex, iTRAQ 8-plex, and TMT 6-plex reagents. The analysis was undertaken because comprehensive comparisons of isobaric mass...

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Bibliographic Details
Main Authors: Casey, T., Khan, J., Bringans, S., Koudelka, T., Takle, P., Downs, R., Livk, A., Syme, Robert, Tan, Kar-Chun, Lipscombe, R.
Format: Journal Article
Published: 2017
Online Access:http://pubs.acs.org/doi/pdf/10.1021/acs.jproteome.5b01154
http://hdl.handle.net/20.500.11937/50901