Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways
Celastrol, a plant triterpene has attracted great interest recently, especially for its potential anti-inflammatory and anti-cancer activities. In the present report, we investigated the effect of celastrol on proliferation of various cancer cell lines. The mechanism, by which this triterpene exerts...
| Main Authors: | , , , , , , , , |
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| Format: | Journal Article |
| Published: |
Springer
2011
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| Online Access: | http://hdl.handle.net/20.500.11937/50124 |