Finding off-targets, biological pathways, and target diseases for chymase inhibitors via structure-based systems biology approach
Off-target binding connotes the binding of a small molecule of therapeutic significance to a protein target in addition to the primary target for which it was proposed. Progressively such off-targeting is emerging to be regular practice to reveal side effects. Chymase is an enzyme of hydrolase class...
| Main Authors: | , , , , , |
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| Format: | Journal Article |
| Published: |
John Wiley & Sons, Inc.
2015
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| Online Access: | http://hdl.handle.net/20.500.11937/50090 |