Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade In Vitro and In Vivo
Cumulative evidences(s) have established that the constitutive activation of STAT3 plays a pivotal role in the proliferation, survival, metastasis, and angiogenesis and thus can contribute directly to the pathogenesis of hepatocellular carcinoma (HCC). Thus, novel agents that can inhibit STAT3 activ...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Journal Article |
| Published: |
American Association for Cancer Research
2012
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| Online Access: | http://hdl.handle.net/20.500.11937/49936 |