Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4
Background: Increasing evidence indicates that the interaction between the CXC chemokine receptor-4 (CXCR4) and its ligand CXCL12 is critical in the process of metastasis that accounts for more than 90% of cancer-related deaths. Thus, novel agents that can downregulate the CXCR4/CXCL12 axis have the...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Journal Article |
| Published: |
BioMed Central Ltd.
2011
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| Online Access: | http://hdl.handle.net/20.500.11937/49916 |